EXPERIMENTAL TECHNIQUES (cont)

For intradermal injections the skin of the back and flank is shaved or cleaned by close clipping and the use of a depilatory preparation.  The skin is prepped with antiseptic solution, stretched tightly, and a small needle is inserted into the dermis.   The material is injected from a tuberculin syringe using a 25 – 27 gauge needle so as to form a small blister or bleb.

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Intradermal injection in the guinea pig

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